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How Zofran Blocks Signals to Your Vomit Center
When taken as directed Zofran or generic Ondansetron blocks the release of serotonin. This is a natural body chemical that is signaled as the cancer treatments (radiation or chemotherapy) are given. By stopping serotonin from attaching to nerves, the vomiting center in your brain will not receive any messages from the chemoreceptor trigger zone (CTZ) so nausea and vomiting can be averted. The generic alternative is not manufactured by the company that makes the brand product.
Conditions Treated by Zofran
Post-operative nausea and vomiting (PONV) in any patient is not something that can be foretold but there are risk factors that may be taken into consideration before undergoing any surgical procedures. If you are experiencing anxiety about the surgery you are about to have, your age and gender, and a previous history of nausea and vomiting following surgery could all be indicators that you are more prone to become nauseous after surgery.
In addition of harm to the surgical site that may be caused by post-op vomiting, there is also a risk of aspirating on your vomit if you are not ambulatory enough to be able to sit up when you vomit. Aspiration pneumonia can be caused as a result of food, saliva, or vomit being breathed into your lungs or airways if you vomit while lying on your back because you are unable to be upright or lean over.
Before You Take Zofran
Tell your doctor if you are pregnant, may become pregnant, or are breastfeeding before taking Zofran so it can be decided if any harm will come to your unborn or nursing baby. Discuss other medical conditions or allergies you have and provide a list of current over the counter or Rx medications you take, including herbal remedies and vitamin or dietary supplements. Taking Zofran with certain drugs could cause unintended or serious side effects.
Until you know how Zofran will affect you, do not make any important decisions and do not drive or perform any tasks that could be considered risky. If you feel confused, weak, or are short of breath after taking Zofran, check with your doctor immediately. As your body becomes used to Zofran, some side effects may disappear. Learn More
Possible Side Effects of Zofran
- Dry mouth
- Trouble sleeping